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Article

Defects in protein folding in congenital hypothyroidism.

Molecular and cellular endocrinology - 5 Feb 2020

Targovnik Héctor M, Scheps Karen G, Rivolta Carina M

Abstract excerpt

Primary congenital hypothyroidism (CH) is the most common endocrine disease in children and one of the most common preventable causes of both cognitive and motor deficits. CH is a heterogeneous group of thyroid disorders in which inadequate production of thyroid hormone occurs due to defects in proteins involved in the gland organogenesis (dysembryogenesis) or in multiple steps of thyroid hormone biosynthesis...

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PMID: 31751626
DOI: 10.1016/j.mce.2019.110638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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