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Hepatitis Delta Virus Alters the Autophagy Process To Promote Its Genome Replication

21 Nov 2019

Abstract excerpt

Hepatitis delta virus is a defective RNA virus that requires hepatitis B virus envelope proteins (HBsAg) to fulfill its life cycle. Thus, HDV can only infect individuals at the same time as HBV (coinfection) or superinfect individuals who are already chronic carriers of HBV. The presence of HDV in the liver accelerates the progression of infection to fibrosis and to hepatic cancer. Since current treatments...

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PMID: 31748400
DOI: 10.1128/jvi.01936-19

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