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Hepatitis C Virus-Induced Autophagy and Host Innate Immune Response

12 Aug 2017

Abstract excerpt

Autophagy is a catabolic process that is important for maintaining cellular homeostasis. This pathway in hepatocytes is stimulated and controlled by the hepatitis C virus (HCV)-upon infection-to promote its own replication. HCV induces autophagy indirectly and directly through different mechanisms and temporally controls the autophagic flux. This enables the virus to maximize its replication and attenuate the...

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PMID: 28805674
DOI: 10.3390/v9080224

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