Article
Clinical impact of low serum free T4 in patients with non-small cell lung cancer treated with nivolumab.
Scientific reports - 19 Nov 2019
Funazo Tomoko Yamamoto, Nomizo Takashi, Ozasa Hiroaki, Tsuji Takahiro, Yasuda Yuto, Yoshida Hironori, Sakamori Yuichi, Nagai Hiroki, Hirai Toyohiro, Kim Young Hak
Abstract excerpt
Nivolumab improves the prognosis of non-small cell lung cancer (NSCLC) but can cause immune-related adverse events (irAEs). Reports have indicated longer progression-free survivals (PFSs) in patients with irAEs than in those without irAEs. We reported associations between programmed death ligand-1 (PD-L1) single nucleotide polymorphisms (SNPs) and PFS after nivolumab treatment. We hypothesized that adverse events...
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