Article
Immunological Status May Predict Response to Nivolumab in Non-small Cell Lung Cancer without Driver Mutations.
Anticancer research - 1 Jul 2017
Nakao Makoto, Muramatsu Hideki, Kagawa Yusuke, Suzuki Yuto, Sakai Yusuke, Kurokawa Ryota, Fujita Kohei, Sato Hidefumi
Abstract excerpt
BACKGROUND/AIM: It remains challenging to select patients with non-small cell carcinoma (NSCLC) for nivolumab monotherapy. We evaluated whether early termination of nivolumab monotherapy correlated with pretreatment neutrophil/lymphocyte ratio (NLR) and prognostic nutritional index (PNI). PATIENTS AND METHODS: Twenty patients received nivolumab monotherapy for NSCLC with wild-type epidermal growth factor receptor...
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