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Article

Live birth in male de novo Kallmann syndrome after cross-generational genetic sequencing.

Journal of assisted reproduction and genetics - 1 Dec 2019

Chan Cindy, Wang Cheng-Wei, Chen Ching-Hui, Chen Chi-Huang

Abstract excerpt

PURPOSE: To present the first case proposing the use of preimplantation genetic testing for monogeneic disorders for Kallmann syndrome, providing comprehensive care in the genomic era of precision medicine. METHODS: Gonadotropin therapy was used for spermatogenesis, followed by in vitro fertilization by intracytoplasmic sperm injection and embryo transfer. Cross-generational targeted next-generation sequencing...

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Source

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Identifiers

PMID: 31741254
DOI: 10.1007/s10815-019-01604-9
PMCID: PMC6911136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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