Article
Staphylococcus aureus Isolated from Skin from Atopic-Dermatitis Patients Produces Staphylococcal Enterotoxin Y, Which Predominantly Induces T-Cell Receptor Vα-Specific Expansion of T Cells.
Infection and immunity - 22 Jan 2020
Aziz Fatkhanuddin, Hisatsune Junzo, Yu Liansheng, Kajimura Junko, Sato'o Yusuke, Ono Hisaya K, Masuda Kanako, Yamaoka Mika, Salasia Siti Isrina Oktavia, Nakane Akio, Ohge Hiroki, Kusunoki Yoichiro, Sugai Motoyuki
Abstract excerpt
While investigating the virulence traits of Staphylococcus aureus adhering to the skin of atopic-dermatitis (AD) patients, we identified a novel open reading frame (ORF) with structural similarity to a superantigen from genome sequence data of an isolate from AD skin. Concurrently, the same ORF was identified in a bovine isolate of S. aureus and designated SElY (H. K. Ono, Y. Sato'o, K. Narita, I. Naito, et al.,...
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