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S. aureus virulence factors decrease epithelial barrier function and increase susceptibility to viral infection

22 Sept 2023

Abstract excerpt

ABSTRACT Individuals with atopic dermatitis (AD) are highly colonized by Staphylococcus aureus and are more susceptible to severe viral complications. We hypothesized that S. aureus secreted virulence factors may alter keratinocyte biology to enhance viral susceptibility through disruption of the skin barrier, impaired keratinocyte differentiation, and/or inflammation. To address this hypothesis, human...

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Share to Allergic Rhinitis and Sensitization
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PMID: 37737609
DOI: 10.1128/spectrum.01684-23

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