Article
LncRNA SNHG8 is identified as a key regulator of acute myocardial infarction by RNA-seq analysis.
Lipids in health and disease - 18 Nov 2019
Zhuo Liu-An, Wen Yi-Tao, Wang Yong, Liang Zhi-Fang, Wu Gang, Nong Mei-Dan, Miao Liu
Abstract excerpt
BACKGROUND: Long noncoding RNAs (lncRNAs) are involved in numerous physiological functions. However, their mechanisms in acute myocardial infarction (AMI) are not well understood. METHODS: We performed an RNA-seq analysis to explore the molecular mechanism of AMI by constructing a lncRNA-miRNA-mRNA axis based on the ceRNA hypothesis. The target microRNA data were used to design a global AMI triple network....
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