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LncRNA PLCD3-OT1 Functions as a CeRNA to Prevent Age-Related Cataract by Sponging miR-224-5p and Regulating PLCD3 Expression

14 Nov 2019

Abstract excerpt

Purpose: Long noncoding RNAs (lncRNAs) are important in disease progression and cellular functions. This study aimed to conduct global lncRNA profiling and characterize the role of lncRNA 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 3-sence RNA 1 (PLCD3-OT1) in the progression of age-related cataract (ARC). Methods: We performed lncRNA expression profiling of lens capsule from ARC groups and...

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Cancer-related molecular mechanisms research
Connexins and lens biology
Intraocular Surgery and Lenses

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31725166
DOI: 10.1167/iovs.19-27211

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