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Article

Interferon regulatory factor 6 is required for proper wound healing in vivo.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Apr 2020

Rhea Lindsey, Canady Franklin J, Le Marc, Reeb Tanner, Canady John W, Kacmarynski Deborah S F, Avvari Rishika, Biggs Leah C, Dunnwald Martine

Abstract excerpt

BACKGROUND: Van der Woude syndrome (VWS) is the most common form of syndromic orofacial cleft caused predominantly by mutations in Interferon Regulatory Factor 6 (IRF6). We previously reported that individuals with VWS have increased risk of wound healing complications following cleft repair compared with individuals with nonsyndromic orofacial clefts (nonsyndromic cleft lip and palate-NSCLP). In vitro, absence...

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Identifiers

PMID: 31724286
DOI: 10.1002/dvdy.134
PMCID: PMC9266192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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