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Episomal Induced Pluripotent Stem Cells: Functional and Potential Therapeutic Applications

14 Nov 2019

Abstract excerpt

The term episomal induced pluripotent stem cells (EiPSCs) refers to somatic cells that are reprogrammed into induced pluripotent stem cells (iPSCs) using non-integrative episomal vector methods. This reprogramming process has a better safety profile compared with integrative methods using viruses. There is a current trend toward using episomal plasmid reprogramming to generate iPSCs because of the improved safety...

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PMID: 31722555
DOI: 10.1177/0963689719886534

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