Article
Identification of a novel monocytic phenotype in Classic Hodgkin Lymphoma tumor microenvironment.
PloS one - 1 Jan 2019
Post Ginell R, Yuan Youzhong, Holthoff Emily R, Quick Charles M, Post Steven R
Abstract excerpt
Classic Hodgkin lymphoma (CHL) characteristically shows few malignant cells in a microenvironment comprised of mixed inflammatory cells. Although CHL is associated with a high cure rate, recent studies have associated poor prognosis with absolute monocyte count in peripheral blood and increased monocyte/macrophages in involved lymph nodes. Thus, the role of monocytic infiltration and macrophage differentiation in...
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