Article
Impact of autism-associated genetic variants in interaction with environmental factors on ADHD comorbidities: an exploratory pilot study.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Dec 2019
Waltes Regina, Freitag Christine M, Herlt Timo, Lempp Thomas, Seitz Christiane, Palmason Haukur, Meyer Jobst, Chiocchetti Andreas G
Abstract excerpt
Attention-deficit/hyperactivity disorder (ADHD) is determined by genetic and environmental factors, and shares genetic risk with ASD. Functional single-nucleotide polymorphisms of the metabotropic glutamatergic signaling pathway are reported to increase the risk for ASD. The aim of this pilot study was to explore the main effects of respective ASD variants as well as their interaction effects with well-replicated...
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