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Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control

8 Nov 2019

Abstract excerpt

Natural hosts of simian immunodeficiency virus (SIV) avoid AIDS despite lifelong infection. Here, we examined how this outcome is achieved by comparing a natural SIV host, African green monkey (AGM) to an AIDS susceptible species, rhesus macaque (RM). To asses gene expression profiles from acutely SIV infected AGMs and RMs, we developed a systems biology approach termed Conserved Gene Signature Analysis (CGSA),...

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PMID: 31704931
DOI: 10.1038/s41467-019-12987-9

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