Article
Prothrombin 3'end Gene Variants in Patients With Sporadic Colon Adenocarcinoma.
Anticancer research - 1 Nov 2019
Cumbo Marija, Tomic Branko, Dunjic Sofija, Jovanovic Tamara, Gvozdenov Maja, Pruner Iva, Aralica Gorana, Kapitanovic Sanja, Cacev Tamara, Djordjevic Valentina
Abstract excerpt
BACKGROUND/AIM: Thrombin plays significant roles in various types of cancer. However, the expression levels of prothrombin, the thrombin precursor, in cancer remain unclear. Variants of the 3'end of the prothrombin gene lead to increased prothrombin expression. This study aimed to analyze prothrombin 3'end gene variants in colon tumor and adjacent normal tissue samples. MATERIALS AND METHODS: The study group...
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