Article
Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration.
eLife - 8 Nov 2019
Gancz Dana, Raftrey Brian C, Perlmoter Gal, Marín-Juez Rubén, Semo Jonathan, Matsuoka Ryota L, Karra Ravi, Raviv Hila, Moshe Noga, Addadi Yoseph, Golani Ofra, Poss Kenneth D, Red-Horse Kristy, Stainier Didier Yr, Yaniv Karina
Abstract excerpt
In recent years, there has been increasing interest in the role of lymphatics in organ repair and regeneration, due to their importance in immune surveillance and fluid homeostasis. Experimental approaches aimed at boosting lymphangiogenesis following myocardial infarction in mice, were shown to promote healing of the heart. Yet, the mechanisms governing cardiac lymphatic growth remain unclear. Here, we identify...
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