Article
Genomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients.
Nature medicine - 1 Nov 2019
Yelin Idan, Flett Kelly B, Merakou Christina, Mehrotra Preeti, Stam Jason, Snesrud Erik, Hinkle Mary, Lesho Emil, McGann Patrick, McAdam Alexander J, Sandora Thomas J, Kishony Roy, Priebe Gregory P
Abstract excerpt
Probiotics are routinely administered to hospitalized patients for many potential indications1 but have been associated with adverse effects that may outweigh their potential benefits2-7. It is particularly alarming that probiotic strains can cause bacteremia8,9, yet direct evidence for an ancestral link between blood isolates and administered probiotics is lacking. Here we report a markedly higher risk of...
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