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Article

The synergistic effect between adult weight changes and CYP24A1 polymorphisms is associated with pre- and postmenopausal breast cancer risk.

Breast cancer research and treatment - 1 Jan 2020

Cao Shang, Wei Feiran, Zhou Jinyi, Zhu Zheng, Li Wei, Wu Ming

Abstract excerpt

PURPOSE: Vitamin D (VD) metabolism regulates adipose tissue, lipogenesis inflammation, and tumor growth. CYP24A1 is the key enzyme for metabolic inactivation of active VD (1,25(OH)2D3). We examined whether common germline single nucleotide polymorphisms (SNPs) in the CYP24A1 gene could affect the association between adult weight gain and breast cancer (BC) risk. METHODS: The population-based case-control study...

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Identifiers

PMID: 31696340
DOI: 10.1007/s10549-019-05484-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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