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Article

Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer.

Journal of biomedical informatics - 1 Dec 2019

Meng Weilin, Ou Wanmei, Chandwani Sheenu, Chen Xin, Black Wynona, Cai Zhaohui

Abstract excerpt

Lines of therapy (LOT) derived from real-world healthcare data not only depict real-world cancer treatment sequences, but also help define patient phenotypes along the course of disease progression and therapeutic interventions. The sequence of prescribed anticancer therapies can be defined as temporal phenotyping resulting from changes in morphological (tumor staging), biochemical (biomarker testing),...

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Identifiers

PMID: 31689549
DOI: 10.1016/j.jbi.2019.103335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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