Article
A single combination gene therapy treats multiple age-related diseases.
Proceedings of the National Academy of Sciences of the United States of America - 19 Nov 2019
Davidsohn Noah, Pezone Matthew, Vernet Andyna, Graveline Amanda, Oliver Daniel, Slomovic Shimyn, Punthambaker Sukanya, Sun Xiaoming, Liao Ronglih, Bonventre Joseph V, Church George M
Abstract excerpt
Comorbidity is common as age increases, and currently prescribed treatments often ignore the interconnectedness of the involved age-related diseases. The presence of any one such disease usually increases the risk of having others, and new approaches will be more effective at increasing an individual's health span by taking this systems-level view into account. In this study, we developed gene therapies based on...
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