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Integrated Network Analysis Reveals FOXM1 and MYBL2 as Key Regulators of Cell Proliferation in Non-small Cell Lung Cancer

15 Oct 2019

Abstract excerpt

BACKGROUND: Loss of control on cell division is an important factor for the development of non-small cell lung cancer (NSCLC), however, its molecular mechanism and gene regulatory network are not clearly understood. This study utilized the systems bioinformatics approach to reveal the “driver-network” involve in tumorigenic processes in NSCLC. METHODS: A meta-analysis of gene expression data of NSCLC was...

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PMID: 31681566
DOI: 10.3389/fonc.2019.01011

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