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Article

The functional mechanisms of mutations in myelodysplastic syndrome.

Leukemia - 1 Dec 2019

Nagata Yasunobu, Maciejewski Jaroslaw P

Abstract excerpt

Overlapping spectrum of mutated genes affected in myelodysplastic syndrome (MDS) and primary acute myeloid leukemia suggest common pathogenic mechanisms. However, the frequencies of specific mutations are significantly different between them, which implies they might determine specific disease phenotype. For instance, there are overrepresentations of mutations in RNA splicing factors or epigenetic regulators in...

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Share to Chromosome Aberrations
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 31673113
DOI: 10.1038/s41375-019-0617-3
PMCID: PMC8370479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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