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Article

A comparison of machine learning classifiers for dementia with Lewy bodies using miRNA expression data.

BMC medical genomics - 30 Oct 2019

Shigemizu Daichi, Akiyama Shintaro, Asanomi Yuya, Boroevich Keith A, Sharma Alok, Tsunoda Tatsuhiko, Sakurai Takashi, Ozaki Kouichi, Ochiya Takahiro, Niida Shumpei

Abstract excerpt

BACKGROUND: Dementia with Lewy bodies (DLB) is the second most common subtype of neurodegenerative dementia in humans following Alzheimer's disease (AD). Present clinical diagnosis of DLB has high specificity and low sensitivity and finding potential biomarkers of prodromal DLB is still challenging. MicroRNAs (miRNAs) have recently received a lot of attention as a source of novel biomarkers. METHODS: In this...

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PMID: 31666070
DOI: 10.1186/s12920-019-0607-3
PMCID: PMC6822471

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