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Day-to-day and within-day biological variation of cell-free DNA

21 Oct 2019

Abstract excerpt

BACKGROUND: Numerous studies have shown that cell-free DNA (cfDNA) levels may serve as a non-invasive biomarker of a broad spectrum of acute and chronic pathologies. However, in order to make clinical decisions based on cfDNA measurements, it is essential to understand the magnitude of biological variation so this variation is not confused with a variation that actually represent a clinically relevant change. The...

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PMID: 31648993
DOI: 10.1016/j.ebiom.2019.10.008

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