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Article

A case for expert curation: an overview of cancer curation in the Clinical Genome Resource (ClinGen).

Cold Spring Harbor molecular case studies - 1 Oct 2019

Ritter Deborah I, Rao Shruti, Kulkarni Shashikant, Madhavan Subha, Offit Kenneth, Plon Sharon E

Abstract excerpt

We describe the Clinical Genome Resource (ClinGen) cancer-related curation activities and the importance of curation to the evolving state of variant interpretation in a clinical context for both pediatric and adult cancer patients. We highlight specific examples from the CDH1 and PTEN Variant Curation Expert Panels (VCEPs) of the FDA-recognized process by which ClinGen VCEPs specify the American College of...

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Identifiers

PMID: 31645350
DOI: 10.1101/mcs.a004739
PMCID: PMC6824250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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