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An efficient protocol to generate placental chorionic plate-derived mesenchymal stem cells with superior proliferative and immunomodulatory properties

17 Oct 2019

Abstract excerpt

BACKGROUND: Placenta-derived MSCs (P-MSCs) represent a promising tool for cell-based therapeutic applications. However, the increasing demand for P-MSCs in clinical trials makes high quality and large number of P-MSCs mandatory. Here, we aim to develop an efficient protocol for P-MSC isolation and culture. METHODS: The modified explant culture (MEC) method by combining an initial mild enzymatic reaction with the...

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PMID: 31623677
DOI: 10.1186/s13287-019-1405-8

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