Article
[Lethal and mutagenic action of incorporated 5-3H-cytosine on extracellular phage lambda].
Radiobiologiia - 1 Jan 2000
Konevega L V, Kalinin V L
Abstract excerpt
A study was made of the lethal and mutagenic effects on extracellular phage gamma of 5-3H-cytosine incorporated into DNA. The efficiencies of inactivation by incorporated 3H were equal for 5-3H-cytosine and [3H-methyl]-thymidine, but the yield of c-mutations for the former was 14 times higher. The lethal and mutagenic effects of incorporated 5-3H-cytosine did not depend on ung mutation of host cells which caused...
Topics
- Bacteriophage lambda
- Cytosine
- DNA Glycosylases
- DNA Repair
- DNA, Viral
- Mutation
- N-Glycosyl Hydrolases
- Tritium
- Ultraviolet Rays
- Uracil-DNA Glycosidase