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The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3

26 Sept 2019

Abstract excerpt

Microbial entrainment of metabolism The metabolism of mammals is synchronized to daily cycles relating to sleep and mealtimes. It is not surprising that the gut microbiota, which aids in digestion, should also display daily cycling. Kuang et al. found that the gut microbiota can mediate daily cycles epigenetically (see the Perspective by Bishehsari and Keshavarzian). The microbiota induces rhythmic expression of...

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PMID: 31604271
DOI: 10.1126/science.aaw3134

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