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Article

Evaluation of EPAS1 variants for association with bovine congestive heart failure

25 Jul 2019

Abstract excerpt

<h4>Background: </h4> Bovine congestive heart failure (BCHF) has become increasingly prevalent in feedlot cattle in the Western Great Plains of North America. BCHF is an untreatable complex condition involving pulmonary hypertension that culminates in right ventricular failure and death. A protein variant of hypoxia-inducible factor 2 alpha (HIF2α, encoded by the endothelial PAS domain-containing protein 1 gene,...

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PMID: 31543958
DOI: 10.12688/f1000research.19951.1

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