Article
Comparable type I interferon score determination from PAXgene and Tempus whole blood RNA collection and isolation systems
15 Aug 2019
Abstract excerpt
OBJECTIVE: Type I interferons (IFN) have important roles in many immune-mediated inflammatory diseases (IMIDs) and are a relatively new therapeutic target. Direct detection of type I IFNs has proved challenging, thus their presence is often inferred from the expression of interferon-stimulated genes (ISGs) and calculation of an interferon score (IS). The objective of this research was to determine if the...
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