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Article

LncRNA PCNAP1 modulates hepatitis B virus replication and enhances tumor growth of liver cancer

1 Jan 2019

Abstract excerpt

Rationale: Hepatitis B virus (HBV) is a major risk factor for liver cancer, in which HBV covalently closed circular DNA (cccDNA) plays crucial roles. However, the effect of pseudogene-derived long noncoding RNAs (lncRNAs) acting as functional regulators of their ancestral gene expression on HBV replication and hepatocellular carcinoma (HCC) remains unclear. In this study, we speculated that the pseudogene-derived...

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PMID: 31410212
DOI: 10.7150/thno.34273

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