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Article

High cGMP and low PDE3A activity are associated with oocyte meiotic incompetence

12 Aug 2019

Abstract excerpt

Resumption of meiosis in mammalian oocytes, defined as oocyte maturation, is stimulated by luteinizing hormone (LH). Fully grown oocytes can also mature spontaneously, upon their release from the ovarian follicle. However, growing oocytes fail to resume meiosis in vitro and the mechanism underlying their meiotic incompetence is unknown. It is commonly accepted that a drop in intraoocyte cyclic guanosine...

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Identifiers

PMID: 31401933
DOI: 10.1080/15384101.2019.1652472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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