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Article

The Removal of Endo- and Enterotoxins From Bacteriophage Preparations

23 Jul 2019

Abstract excerpt

The production of phages for therapeutic purposes demands fast, efficient and scalable purification procedures. Phage lysates have a wide range of impurities, of which endotoxins of gram-negative bacteria and protein toxins produced by many pathogenic bacterial species are harmful to humans. The highest allowed endotoxin concentration for parenterally applied medicines is 5 EU/kg/h. The aim of this study was to...

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Identifiers

PMID: 31396188
DOI: 10.3389/fmicb.2019.01674

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