Article
Some studies on idiotypes and anti-idiotypic reactions and receptors in anti-allo-MHC T-cell immunity.
Annales d'immunologie - 1 Jan 2000
Binz H, Frischknecht H, Wigzell H
Abstract excerpt
The fine specificity of immunocompetent T lymphocytes is reflected on their outer surface by their display of idiotype-positive receptor molecules. Interference with these structures using antiidiotypic reagents may trigger or eliminate the cell depending on the external conditions. When analyzing the distribution pattern of idiotypes on murine allo-MHC activated T blasts it was found that proliferating "helper"...
Topics
- Animals
- Antibodies, Anti-Idiotypic
- Binding Sites
- Cytotoxicity, Immunologic
- H-2 Antigens
- Immunoglobulin Idiotypes
- Isoantigens
- Lymphocyte Activation
- Major Histocompatibility Complex
- Mice
- Phenotype