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Abnormal hippocampal structure and function in juvenile myoclonic epilepsy and unaffected siblings

24 Jul 2019

Abstract excerpt

Juvenile myoclonic epilepsy is the most common genetic generalized epilepsy syndrome, characterized by a complex polygenetic aetiology. Structural and functional MRI studies demonstrated mesial or lateral frontal cortical derangements and impaired fronto-cortico-subcortical connectivity in patients and their unaffected siblings. The presence of hippocampal abnormalities and associated memory deficits is...

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PMID: 31365054
DOI: 10.1093/brain/awz215

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