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Article

Melatonin promotes human oocyte maturation and early embryo development by enhancing clathrin‐mediated endocytosis

30 Jul 2019

Abstract excerpt

Abstract Embryo development potential and reproductive clinical outcomes are all deeply rooted in oocyte maturation. Melatonin has been reported to promote oocyte maturation as an antioxidant in nonprimate species. Its antioxidative functions also help reduce plasma membrane rigidity, which facilitates clathrin‐mediated endocytosis (CME). Whether melatonin has effects on human oocyte maturation by regulating CME...

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PMID: 31361919
DOI: 10.1111/jpi.12601

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