Article
High-risk, Expression-Based Prognostic Long Noncoding RNA Signature in Neuroblastoma
1 Apr 2018
Abstract excerpt
Abstract Background Current clinical risk factors stratify patients with neuroblastoma (NB) for appropriate treatments, yet patients with similar clinical behaviors evoke variable responses. MYCN amplification is one of the established drivers of NB and, when combined with high-risk displays, worsens outcomes. Growing high-throughput transcriptomics studies suggest long noncoding RNA (lncRNA) dysregulation in...
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