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miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples

26 Oct 2011

Abstract excerpt

PURPOSE: More accurate assessment of prognosis is important to further improve the choice of risk-related therapy in neuroblastoma (NB) patients. In this study, we aimed to establish and validate a prognostic miRNA signature for children with NB and tested it in both fresh frozen and archived formalin-fixed paraffin-embedded (FFPE) samples. EXPERIMENTAL DESIGN: Four hundred-thirty human mature miRNAs were...

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PMID: 22031095
DOI: 10.1158/1078-0432.ccr-11-0610

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