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Article

Reversal of Multidrug Resistance in Cancer by Multi-Functional Flavonoids

12 Jun 2019

Abstract excerpt

Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have been developed, but most of them fail in clinical trials due to severely adverse effects. Recently, certain natural products have been reported to overcome MDR, including flavonoids which are abundant in plants, foods, and herbs. The...

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PMID: 31245292
DOI: 10.3389/fonc.2019.00487

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