Article
Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3
26 Jun 2019
Abstract excerpt
How developmental programs reactivate in regeneration is a fundamental question in biology. We addressed this question through the study of Wound Induced Hair follicle Neogenesis (WIHN), an adult organogenesis model where stem cells regenerate de novo hair follicles following deep wounding. The exact mechanism is uncertain. Here we show that self-noncoding dsRNA activates the anti-viral receptor toll like...
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