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Exploring the Relationship of Relative Telomere Length and the Epigenetic Clock in the LipidCardio Cohort

21 Jun 2019

Abstract excerpt

Telomere length has been accepted widely as a biomarker of aging. Recently, a novel candidate biomarker has been suggested to predict an individual’s chronological age with high accuracy: The epigenetic clock is based on the weighted DNA methylation (DNAm) fraction of a number of cytosine-phosphate-guanine sites (CpGs) selected by penalized regression analysis. Here, an established methylation-sensitive single...

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PMID: 31234328
DOI: 10.3390/ijms20123032

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