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Article

The Effects of Plumbagin on Pancreatic Cancer: A Mechanistic Network Pharmacology Approach

23 Jun 2019

Abstract excerpt

BACKGROUND This study aimed to use a network pharmacology approach to establish the effects of plumbagin on pancreatic cancer (PC) and to predict core targets and biological functions, pathways, and mechanisms of action. MATERIAL AND METHODS Genes associated with the pathogenesis of PC were obtained from a database of gene-disease associations (DisGeNET). Putative genes associated with plumbagin were identified...

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PMID: 31230062
DOI: 10.12659/msm.917240

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