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Article

Epigenetic activation and memory at a <i>TGFB2</i> enhancer in systemic sclerosis

19 Jun 2019

Abstract excerpt

NF-κB and BRD4 epigenetically activate a TGFB2 enhancer to lock sclerotic patient fibroblasts into a profibrotic synthetic state.

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Identifiers

PMID: 31217334
DOI: 10.1126/scitranslmed.aaw0790

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