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Article

Chronic obstructive pulmonary disease upper airway microbiota alpha diversity is associated with exacerbation phenotype: a case-control observational study.

Respiratory research - 7 Jun 2019

Pragman Alexa A, Knutson Katherine A, Gould Trevor J, Isaacson Richard E, Reilly Cavan S, Wendt Chris H

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) frequent exacerbators (FE) suffer increased morbidity and mortality compared to infrequent exacerbators (IE). The association between the oral and sputum microbiota and exacerbation phenotype is not well defined. The objective of this study was to determine key features that differentiate the oral and sputum microbiota of FEs from the microbiota of IEs...

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Identifiers

PMID: 31174538
DOI: 10.1186/s12931-019-1080-4
PMCID: PMC6555967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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