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Article

FOX-A1 contributes to acquisition of chemoresistance in human lung adenocarcinoma via transactivation of SOX5

27 May 2019

Abstract excerpt

BACKGROUND: Chemoresistance is a major obstacle for the effective treatment of lung adenocarcinoma (LAD). Forkhead box (FOX) proteins have been demonstrated to play critical roles in promoting epithelial-mesenchymal transition (EMT) and chemoresistance. However, whether FOX proteins contribute to the acquisition of EMT and chemoresistance in LAD remains largely unknown. METHODS: FOX-A1 expression was measured in...

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PMID: 31147293
DOI: 10.1016/j.ebiom.2019.05.046

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