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Transferable linezolid resistance genes (optrA and poxtA) in enterococci derived from livestock compost at Japanese farms

7 Feb 2024

Abstract excerpt

OBJECTIVES: Linezolid is a last-resort antimicrobial in human clinical settings to treat multidrug-resistant Gram-positive bacterial infections. Mobile linezolid resistance genes (optrA, poxtA, and cfr) have been detected in various sources worldwide. However, the presence of linezolid-not-susceptible bacteria and mobile linezolid resistance genes in Japan remains uncertain. Therefore, we clarified the existence...

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PMID: 38336229
DOI: 10.1016/j.jgar.2024.01.022

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