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Article

miR-141-5p regulate ATF2 via effecting MAPK1/ERK2 signaling to promote preeclampsia

8 May 2019

Abstract excerpt

OBJECTIVE: Preeclampsia is a pregnancy-specific syndrome characterized by hypertension and proteinuria. Impaired trophoblast invasion partly modulated by abnormal MAPK1/ERK2 signaling played important roles in the pathological process of preeclampsia. The objective of this study is to investigate miR-141-5p regulate ATF2 via effecting MAPK1/ERK2 signaling to promote preeclampsia. STUDY DESIGN: The maternal...

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PMID: 31075732
DOI: 10.1016/j.biopha.2019.108953

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