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Article

Up-regulation of miR-517-5p inhibits ERK/MMP-2 pathway: potential role in preeclampsia.

1 Oct 2018

Abstract excerpt

OBJECTIVE: To investigate the potential role of miRNA-517-5p in preeclampsia and its underlying mechanism. MATERIALS AND METHODS: Placenta samples were obtained from 20 women with preeclampsia and 20 women with normal pregnancies. Expression level of miR-517-5p in placenta samples and JAR cells was detected. MiRNA-517-5p mimics or inhibitor was transfected in JAR cells, followed by detection of proliferative and...

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Share to Pregnancy and preeclampsia studies
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PMID: 30402831
DOI: 10.26355/eurrev_201810_16134

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