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Article

GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

7 May 2019

Abstract excerpt

Abstract Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we investigated common genetic variants associated with DLB in a large European multisite sample. We performed a genome wide association study in Norwegian and European cohorts of 720 DLB...

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PMID: 31065058
DOI: 10.1038/s41598-019-43458-2

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